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Fibromuscular Dysplasia in a Young Man
Masashi Koga1, Osami Kawarada2, Mari Kaneki1
1Department of Cardiology, St Marianna University School of Medicine, Kawasaki, Japan.
JACC. Case Reports
|August 8, 2025
Summary
Fibromuscular dysplasia (FMD), a vascular condition typically seen in women, can affect men. This case highlights the need to consider FMD in young men with nonatherosclerotic vascular disease.
Area of Science:
- Vascular Medicine
- Pathology
Background:
- Fibromuscular dysplasia (FMD) is a noninflammatory vascular condition.
- FMD predominantly affects women, making male cases atypical.
Purpose of the Study:
- To report a case of FMD in a young man.
- To emphasize the importance of considering FMD in atypical presentations.
Main Methods:
- Case presentation of a 42-year-old man with claudication.
- Vascular imaging including coronary and peripheral arteries.
- Histopathological confirmation of FMD.
Main Results:
- The patient presented with superficial femoral artery occlusion, tortuous coronary arteries, and radial artery involvement.
- Histopathology confirmed FMD, despite the patient's sex and vascular distribution being atypical for the condition.
Conclusions:
- Fibromuscular dysplasia should be considered in young men presenting with nonatherosclerotic vascular disease.
- Multimodal imaging and biopsy are essential for accurate diagnosis of FMD.
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