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Updated: Sep 12, 2025

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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
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Simultaneous Cardiac Surgery for Infective Endocarditis and Liver Transplantation in End-Stage Liver Disease
Erasmus Mutabi1, Ben Boyarko1, Emerson Rowe1
1Department of Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
JACC. Case Reports
|August 8, 2025
Summary
Simultaneous heart and liver surgery for infective endocarditis (IE) and end-stage liver disease is challenging but feasible. A multidisciplinary approach can lead to successful outcomes in select high-risk patients.
Area of Science:
- Cardiovascular Surgery
- Hepatobiliary Surgery
- Transplant Surgery
Background:
- Concurrent infective endocarditis (IE) and end-stage liver disease (ESLD) pose significant perioperative risks.
- Patients with ESLD often have comorbidities that complicate cardiac surgical procedures.
Observation:
- A 53-year-old male with decompensated cirrhosis and IE presented with severe aortic regurgitation and a vegetation extending into the aortomitral curtain.
- The patient underwent a simultaneous orthotopic liver transplantation and cardiac surgery.
Findings:
- The complex procedure involved double valve replacement and aortomitral curtain reconstruction with patch repair.
- The simultaneous surgery was successfully completed, demonstrating feasibility in a high-risk patient.
Implications:
- This case highlights the potential benefit of a single-stage, multidisciplinary approach for select patients with concurrent IE and ESLD.
- Successful outcomes depend on close collaboration between cardiac and transplant surgical teams.
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