Hybrid Revascularization Approach in a Patient With Cancer Metastatic to the Sternum

Shengyi Fu1, Mohammed Elzeneini1, Richard A Kerensky1

  • 1Department of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.

JACC. Case Reports
|August 8, 2025
PubMed

Insights

Hybrid revascularization offers a less invasive option for multivessel coronary artery disease. This approach proved safe and effective for a high-risk patient, demonstrating its potential in complex cases.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology

Background:

  • Hybrid revascularization presents a minimally invasive alternative to traditional coronary artery bypass grafting for multivessel coronary artery disease.
  • Despite its benefits, adoption is limited by technical complexity, logistical hurdles, and concerns regarding long-term graft patency.

Observation:

  • A 68-year-old male patient with a history of prostate cancer and bone metastasis presented with accelerated angina.
  • Diagnostic left heart catheterization confirmed multivessel coronary disease.
  • The patient underwent a staged hybrid surgical and percutaneous revascularization procedure.

Findings:

  • The hybrid intervention was technically successful.
  • The patient experienced significant symptomatic relief post-procedure.
  • Successful recovery to baseline functional status was achieved.

Implications:

  • This case highlights the efficacy of a tailored hybrid approach for high-risk patients with comorbidities.
  • Hybrid revascularization can be safely considered for complex cases on an individualized basis.
Abstract