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Updated: Sep 12, 2025

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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
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Innovative Use of Fusion Imaging for Percutaneous Closure of Post-Myocardial Infarction Ventricular Septal Rupture.
Mustafa Alkhawam1, Ali J Ebrahimi1, Navin C Nanda1
1Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA.
JACC. Case Reports
|August 8, 2025
Summary
Fusion imaging (FI) guided percutaneous closure of post-myocardial infarction (MI) ventricular septal rupture (VSR) offers a precise and rapid approach. This technique enhances device deployment accuracy in critically ill patients, reducing procedural risks.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Imaging
Background:
- Ventricular septal rupture (VSR) following myocardial infarction (MI) is a rare but life-threatening complication.
- Percutaneous closure is the preferred intervention, especially in unstable patients.
Observation:
- A 60-year-old male presented with cardiogenic shock and basal VSR post-MI stent placement.
- Echocardiography confirmed a significant left-to-right shunt through the VSR.
Findings:
- Fusion imaging (FI), integrating echocardiography and fluoroscopy, guided the percutaneous closure.
- A 16-mm Amplatzer device was successfully deployed with minimal residual shunt.
- FI enhanced real-time visualization, improving procedural precision.
Implications:
- FI offers a novel, accurate approach for percutaneous VSR closure in high-risk patients.
- This technique can potentially reduce radiation exposure and procedural duration.
- FI facilitates rapid and precise interventions in critically ill cardiovascular patients.

