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Advancing HIV and Cancer Research: Implementing an AIDS and Cancer Specimen Resource in Latin America
Larissa L S Scholte1, Evandro S Mello2, Karim Yaqub Ibrahim3,4
1Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, District of Columbia, USA.
Biopreservation and Biobanking
|August 8, 2025
Summary
The AIDS and Cancer Specimen Resource established a biorepository in Brazil for HIV-associated cancers. This resource provides vital biospecimens and data from Latin American populations to advance cancer research in people with HIV.
Area of Science:
- Oncology
- Infectious Diseases
- Biorepository Science
Background:
- High burden of HIV-associated cancers in Latin America necessitates localized research resources.
- Limited access to well-annotated biospecimens from Latin American populations hinders HIV/cancer research.
- Need for a dedicated biorepository adhering to international ethical and regulatory standards.
Purpose of the Study:
- To detail the establishment of a dedicated HIV-associated cancer biorepository in São Paulo, Brazil.
- To address the need for high-quality, well-annotated biospecimens from Latin American populations.
- To support research on cancer pathogenesis, viral reservoirs, and clinical outcomes in people with HIV (PWH).
Main Methods:
- Systematic collection and linkage of biospecimens with demographic and clinical data.
- Implementation of sample acquisition, infrastructure development, and inventory management systems.
- Adherence to international ethics, community engagement, and regulatory standards.
Main Results:
- Established a functional biorepository network supporting HIV-associated cancer research in Brazil.
- Created a valuable resource of linked biospecimens and clinical data for Latin American populations.
- Facilitated research collaborations and strengthened regional research capacity.
Conclusions:
- The new biorepository expands access to critical biospecimens for HIV/cancer research.
- This initiative supports research to improve outcomes for people with HIV and cancer.
- Strengthened research infrastructure and capacity in the Latin American region.
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