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Navigating the Colorectal Cancer Maze: Unveiling Pathways To Diagnosis, Management, Pathophysiology and Prevention
Khalid Ali Mohammed Al Kamzari1, Constantina Constantinou2
1Department of Basic and Clinical Sciences, University of Nicosia Medical School, 21 Ilia Papakyriakou, P.O. Box 24005, Engomi, Nicosia, 2414, CY-1700, Cyprus.
Colorectal cancer (CRC) is a major global health concern. Early detection through screening and lifestyle changes are key to reducing CRC incidence and mortality.
Area of Science:
- Oncology
- Public Health
- Gastroenterology
Background:
- Colorectal cancer (CRC) is a leading cause of cancer-related death globally.
- CRC develops from benign polyps over time, influenced by genetic factors.
- Understanding CRC epidemiology, risk factors, and management is crucial.
Purpose of the Study:
- To review current knowledge on colorectal cancer.
- To summarize epidemiology, risk factors, diagnostics, treatments, and prevention.
- To identify knowledge gaps for future research.
Main Methods:
- Comprehensive literature review of colorectal cancer research.
- Analysis of epidemiological data and risk factors.
- Evaluation of diagnostic and therapeutic strategies.
Main Results:
- Lifestyle factors (diet, smoking, obesity) significantly impact CRC risk.
- Colonoscopy, imaging, and biopsies are key diagnostic tools.
- Treatment varies from surgery in early stages to chemotherapy and targeted therapies in advanced stages.
Conclusions:
- Advances in CRC diagnostics and treatments show promise.
- Further research is needed to refine management and screening strategies.
- Lifestyle modifications and early screening are vital for reducing CRC burden.
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