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Effect of hypertension on clinical outcomes in ischemic colitis

Huahui Zhang1,2, Zijia Ma2, Xianfeng Qiu1

  • 1Department of Gastroenterology, The Affiliated Lianyungang Hospital of Xuzhou Medical University/The First People's Hospital of Lianyungang, Lianyungang, China.

Annals of Medicine
|August 9, 2025
PubMed

Insights

Hypertension exacerbates symptoms and endoscopic findings in patients with ischemic colitis (IC). However, this condition does not appear to impact overall clinical outcomes or mortality rates in the studied population.

Area of Science:

  • Gastroenterology
  • Clinical Medicine
  • Epidemiology

Background:

  • Ischemic colitis (IC) is a condition affecting the colon.
  • Hypertension is a common comorbidity in various diseases.
  • The impact of hypertension on IC requires further investigation.

Purpose of the Study:

  • To investigate the effect of hypertension on ischemic colitis.
  • To compare clinical features and outcomes between hypertensive and non-hypertensive IC patients.

Main Methods:

  • Retrospective study of 213 ischemic colitis patients.
  • Patients divided into hypertension (HP) and non-hypertension (NHP) groups.
  • Analysis of clinical features, biochemical indicators, endoscopic findings, pain relief time, hospital stay, operation rate, gangrenous IC incidence, and 30-day mortality.

Main Results:

  • Hypertensive patients were older and experienced more severe abdominal pain.
  • The incidence of ulceration was significantly higher in the hypertension group.
  • No significant differences were observed in pain relief time, hospital stay, operation rate, gangrenous IC incidence, or 30-day mortality.

Conclusions:

  • Hypertension is associated with worse clinical symptoms and endoscopic findings in ischemic colitis.
  • Hypertension does not significantly affect the clinical outcomes of ischemic colitis.
Abstract

Keywords:
Abdominal paincolonoscopyhypertensionischemic colitisrectal bleeding

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