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Updated: Sep 12, 2025

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
Published on: June 20, 2025
Enhanced hyper tuning using bioinspired-based deep learning model for accurate lung cancer detection and
Jyoti Kumari1, Sapna Sinha1, Laxman Singh2
1Department of Computer Science and Engineering, Amity Institute of Information Technology, Amity University, Noida, Uttar Pradesh, India.
Abstract:
Lung cancer (LC) is one of the leading causes of cancer related deaths worldwide and early recognition is critical for enhancing patient outcomes. However, existing LC detection techniques face challenges such as high computational demands, complex data integration, scalability limitations, and difficulties in achieving rigorous clinical validation. This research proposes an Enhanced Hyper Tuning Deep Learning (EHTDL) model utilizing bioinspired algorithms to overcome these limitations and improve accuracy and efficiency of LC detection and classification. The methodology begins with the Smooth Edge Enhancement (SEE) technique for preprocessing CT images, followed by feature extraction using GLCM-based Texture Analysis. To refine the features and reduce dimensionality, a Hybrid Feature Selection approach combining Grey Wolf optimization (GWO) and Differential Evolution (DE) is employed. Precise lung segmentation is performed using Mask R-CNN to ensure accurate delineation of lung regions. A Deep Fractal Edge Classifier (DFEC) is introduced, consisting of five fractal blocks with convolutional layers and pooling to progressively learn LC characteristics. The proposed EHTDL model achieves remarkable performance metrics, including 99% accuracy, 100% precision, 98% recall, and 99% F1-score, demonstrating its robustness and effectiveness. The model's scalability and efficiency make it suitable for real-time clinical application offering a promising solution for early LC detection and significantly enhancing patient care.

