Harnessing the potential of ethnopharmacology for future medicines
Bhushan Patwardhan1, Urmila Aswar2
1Department of Health Sciences, Savitribai Phule Pune University, Pune, 411007, India.
Aim:
This article explores the modern significance of ethnopharmacology in overcoming drug discovery challenges and highlights its potential when combined with cutting-edge technologies to drive innovative therapeutic developments.
Material And Methods:
A comprehensive literature search was conducted across multiple databases, including PubMed, ScienceDirect, Scopus, utilizing keywords such as ethnopharmacology, traditional medicine, drug discovery and development, reverse pharmacology, modern techniques of drug discovery, ethnopharmacology and antibiotic resistance or metabolic disease or ageing.
Results:
Drug discovery faces significant challenges, including lengthy timelines, exorbitant costs, high risk of failure, and the potential for adverse drug reactions. Ethnopharmacology bridges traditional medicinal knowledge with modern scientific methodologies, uncovering novel drug candidates and emphasizing multi-target therapeutic approaches. The discipline offers promising solutions for metabolic diseases, antimicrobial resistance, and chronic conditions by leveraging bioactive compounds from natural sources. Furthermore, advancements in reverse pharmacology, Ayurgenomics and systems biology enhance the discovery and development, enabling personalized and safer treatments.
Conclusion:
Ethnopharmacology's integration with cutting-edge technologies presents a transformative path toward synergistic formulation discovery and personalized therapeutics.
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