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Updated: Sep 12, 2025

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Left ventricular wire pacing technique in transcatheter aortic valve replacement
Mengnan Shi1, Hang Zhang2, Jinghui An2
1Department of Cardiology, The Second Hospital of Hebei Medical University, No. 215 of Heping West Road, Xinhua District, Shijiazhuang, 050000, China.
The left ventricular lead pacing technique is safe and effective for transcatheter aortic valve replacement (TAVR). This method showed successful valve implantation and no major adverse events in a 3-month follow-up.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Transcatheter aortic valve replacement (TAVR) is a crucial procedure for aortic stenosis.
- Optimizing TAVR procedural safety and efficacy remains a key focus in cardiac interventions.
- Left ventricular lead pacing offers a potential alternative for procedural management during TAVR.
Purpose of the Study:
- To evaluate the safety and effectiveness of the left ventricular lead pacing technique during TAVR.
- To assess intraoperative pacing success and post-procedural outcomes.
- To determine the impact on complication rates, surgical metrics, and patient recovery.
Main Methods:
- A cohort of 30 patients undergoing TAVR with left ventricular lead pacing was studied.
- Key metrics included intraoperative pacing effectiveness, valve implantation success, complication frequency, procedure duration, radiation dose, and costs.
- Postoperative adverse events (mortality, stroke, myocardial infarction) were monitored for three months.
Main Results:
- Successful TAVR with left ventricular lead pacing was achieved in all patients.
- 29 transfemoral and 1 transcarotid approach cases were completed, with 32 valves implanted, including 2 "valve-in-valve" procedures.
- No significant paravalvular leaks or conduction blocks requiring pacemakers were observed; mild leaks occurred in 25 cases. No major adverse events were reported within 3 months.
Conclusions:
- The left ventricular lead pacing technique is a safe and reliable method for TAVR.
- This approach facilitates successful valve implantation and is associated with favorable short-term outcomes.
- Further research may explore its broader application in TAVR procedures.
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