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Updated: Sep 11, 2025
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Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
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Risk factors for hypocalcemia after total thyroidectomy: a narrative review
1General Surgery, China Medical University, Shenyang, Liaoning, China.
Peerj
|August 11, 2025
Summary
Postoperative hypocalcemia after total thyroidectomy is common and impacts patient outcomes. Preventing parathyroid injury during surgery is key to avoiding this complication.
Area of Science:
- Endocrinology
- Surgical Oncology
Background:
- Hypocalcemia is a frequent complication following total thyroidectomy.
- It significantly impacts patients' postoperative quality of life and long-term prognosis.
Purpose of the Study:
- To review risk factors associated with postoperative hypocalcemia.
- To assess the predictive ability of parathyroid hormone (PTH) levels for hypocalcemia.
- To discuss methods for protecting parathyroid glands during surgery.
Main Methods:
- Review of studies on risk factors like age, sex, magnesium, vitamin D, pathology, and parathyroid injury.
- Analysis of preoperative and postoperative PTH levels and their changes.
- Evaluation of tracer techniques for parathyroid gland protection.
Main Results:
- Parathyroid injury is identified as the most significant risk factor for postoperative hypocalcemia.
- Preoperative and postoperative PTH levels can predict hypocalcemia.
- Tracer techniques may aid in protecting parathyroid glands in situ.
Conclusions:
- Minimizing intraoperative parathyroid injury is crucial for preventing postoperative hypocalcemia.
- Surgeons must be knowledgeable in techniques to avoid parathyroid damage.
- Effective prevention strategies can improve patient outcomes after thyroidectomy.
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