Related Experiment Video
Updated: Sep 11, 2025

Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
Published on: January 29, 2014
A Case of Primary Cold Agglutinin-Mediated Hemolytic Anemia Successfully Treated with Steroids
Thayani Raja1, Pakkiyaretnam Mayurathan1,2, Sithy Sabrina1
1University Medical Unit, Teaching Hospital, Batticaloa, LKA.
Abstract:
Cold agglutinin disease (CAD) is an uncommon subtype of autoimmune hemolytic anemia (AIHA). Cold agglutinin syndrome (CAS) may occur secondary to infections, autoimmune disorders, or malignancies, which must be ruled out to establish a diagnosis of primary CAD. Typically, cold autoimmune hemolytic anemia (cAIHA) is unresponsive to corticosteroid therapy. However, we report a case of a 69-year-old male patient with primary CAD who was successfully treated with corticosteroids. The patient demonstrated marked clinical improvement and normalization of hemolytic markers following treatment with prednisone.
More Related Videos
05:18Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
11:55Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
Published on: March 14, 2011
Related Concept Videos
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Blood Typing
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...