Related Experiment Video
Updated: Sep 11, 2025
Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
Published on: September 27, 2024
Pulmonary function test and carotid intima-media thickness in chronic obstructive pulmonary disease
Shahabaddin Sorouri1, Maryam Naseri2, Sepideh Hejazi1
1Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Background:
Studies have shown that carotid intima-media thickness (CIMT) is an indicator of cardiovascular events and mortality and its increase has correlation with severe airflow obstruction in patients with COPD. The aim of this study was to investigate the association between pulmonary function and CIMT in COPD patients.
Methods:
This study was performed on two groups of patients with and without COPD (cases & controls) who were referred to pulmonary clinics. Demographic, clinical, and laboratory tests were recorded in questionnaire. Spirometry was performed in cases and FVC, FEV1, and FEV1/FVC were measured. CIMT was determined via ultrasound.
Results:
Our results indicated that right carotid IMT was 0.51±0.112 mm and 0.65±0.131 mm in the control and case groups, respectively (p< 0.001). Left CIMT was 0.48±0.089 mm and 0.68±0.113 mm in the control and case groups, respectively (p< 0.001). FEV1 and FEV1/FVC had an inverse and significant correlation with IMT of the carotid (both right and left carotid).
Conclusion:
The results indicated an inverse association between carotid IMT and lung function test in COPD patients.
Related Concept Videos
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
01:25Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation