Cardiovascular involvement in Sweet's syndrome: A practical review

Area of Science:

• Dermatology
• Cardiology
• Internal Medicine

Background:

• Sweet's syndrome (acute febrile neutrophilic dermatosis) is characterized by fever, skin lesions, and neutrophilia.
• Extracutaneous manifestations, particularly cardiovascular involvement, are common but underreported.
• Existing literature on cardiac involvement in Sweet's syndrome is limited, complicating clinical practice.

Purpose of the Study:

• To underscore the significance of cardiovascular implications in Sweet's syndrome.
• To emphasize the need for increased clinical suspicion for concurrent cardiac conditions.
• To guide diagnostic and management strategies for Sweet's syndrome with cardiovascular involvement.

Main Methods:

• Literature review focusing on Sweet's syndrome and cardiovascular manifestations.
• Clinical case analysis (if applicable, though not explicitly stated in the abstract).
• Synthesis of current understanding and identification of knowledge gaps.

Main Results:

• Sweet's syndrome frequently presents with extracutaneous, including cardiovascular, complications.
• Cardiovascular involvement can manifest as arteritis, myocarditis, or coronary artery disease.
• Diagnosis and management are often challenging due to limited data.

Conclusions:

• A high index of suspicion is necessary for diagnosing Sweet's syndrome with cardiovascular involvement.
• Standardized treatment and monitoring protocols are needed.
• Further research is essential to clarify the relationship and management of cardiac issues in Sweet's syndrome.