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Abdominal Necrotizing Fasciitis Secondary to the Intramuscular Injection of Permethrin: An Uncommon Case Presentation

Juan M Gómez-Rodríguez1, Jorge L Estévez-Arrizon1, Luis E Ocampo-Guzmán1

  • 1General Surgery, Hospital Regional Universitario de Colima, Colima, MEX.

Cureus
|August 11, 2025
PubMed

Insights

Necrotizing fasciitis, a severe bacterial infection, developed in a woman after self-injecting permethrin. Prompt surgical treatment and antibiotics led to recovery, highlighting permethrin

Area of Science:

  • Toxicology
  • Infectious Diseases
  • Dermatology

Background:

  • Necrotizing fasciitis is a life-threatening soft tissue infection.
  • Self-injection of substances can lead to severe complications.

Observation:

  • A 40-year-old woman with schizophrenia self-injected permethrin intramuscularly.
  • She presented with abdominal pain, fever, and a fluid collection on CT scan.

Findings:

  • The patient was diagnosed with necrotizing fasciitis.
  • Surgical debridement and antibiotic therapy resulted in a favorable outcome.

Implications:

  • Permethrin injection may cause local toxicity and tissue damage.
  • Early diagnosis and intervention are critical for managing this condition.
  • Prevention of toxic substance misuse is essential.
Keywords:
abdominal wallinsecticidesintramuscular injectionnecrotizing fasciitispyrethroids

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