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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

755
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Video

Updated: Sep 11, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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An exceptional presentation of malignant glaucoma: case report.

Hamza Lazaar1, Mourad Labhar1, Zineb Filali1

  • 1Ophthalmology department "A", Ibn Sina University Hospital (hôpital des spécialités), Mohammed V University, Rabat, Morocco.

Annals of Medicine and Surgery (2012)
|August 11, 2025
PubMed
Summary

This study reports a rare case of malignant glaucoma occurring 15 years after cataract surgery, presenting with anterior iris displacement and an intact ciliary-lenticular block. Prompt intervention is key to preventing vision loss in this challenging condition.

Keywords:
acute angle closureangle-closure glaucomacataract surgeryophthalmology

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Area of Science:

  • Ophthalmology
  • Surgical Complications
  • Glaucoma Research

Background:

  • Angle closure is a rare but serious complication after cataract surgery, particularly in pseudophakic patients with posterior chamber implants.
  • It can manifest as malignant glaucoma or pseudophakic pupillary block, typically occurring soon after surgery but occasionally years later.
  • The condition involves anterior displacement of the lens-iris-diaphragm complex.

Observation:

  • A case of an 83-year-old female presenting with a painful red eye and reduced visual acuity 15 years post-cataract surgery.
  • Examination revealed elevated intraocular pressure, corneal edema, peripheral athalamia, and importantly, an intact ciliary-lenticular block.
  • This presentation is exceptional due to the delayed onset and the specific anatomical findings.

Findings:

  • This is the first reported case of malignant glaucoma with an intact ciliary-lenticular block presenting 15 years after cataract surgery.
  • The underlying pathophysiology remains unknown, highlighting a gap in current understanding.
  • Management is challenging, with no established consensus, but early anterior vitrectomy and iridozonulohyaloidotomy are suggested.

Implications:

  • This case expands the known timeline for malignant glaucoma post-cataract surgery.
  • It underscores the need for vigilance in diagnosing and managing delayed angle closure, even with unusual features.
  • Further research into the pathophysiology and optimal management strategies for such rare presentations is warranted to improve patient outcomes.