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Updated: Sep 11, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Artificial Intelligence in Health Promotion and Disease Reduction: Rapid Review.
Farzaneh Yousefi1,2, Florian Naye3, Steven Ouellet2
1Department of Health Management, Policy, and Economics, Faculty of Management and Medical Information Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Artificial intelligence (AI) effectively promotes healthy lifestyles and reduces disease by leveraging mobile applications. This review highlights AI
Area of Science:
- Public Health
- Health Informatics
- Digital Health
Background:
- Chronic diseases pose a significant global mortality burden, often driven by behavioral risk factors.
- Artificial intelligence (AI) offers transformative potential in health promotion and disease reduction.
- AI applications improve early detection, encourage lifestyle modifications, and alleviate healthcare system economic strain.
Purpose of the Study:
- To investigate the role of AI in health promotion and disease reduction within Organisation for Economic Co-operation and Development (OECD) countries.
- To synthesize current evidence on AI-driven health initiatives.
Main Methods:
- A rapid literature review was conducted, searching MEDLINE (OVID) and CINAHL for studies published between 2019 and 2024.
- Two independent reviewers screened 3442 publications, assessing 22 included studies for data extraction.
- Data on study characteristics, interventions, and purposes were synthesized using narrative summaries.
Main Results:
- The review included 22 studies, primarily from the United States, focusing on lifestyle modifications (diet, smoking cessation, physical activity, mental health) and metabolic disease reduction.
- AI-powered mobile apps were the predominant intervention type, demonstrating positive outcomes in engagement, behavior change, and health indicators like blood pressure and glycemia.
- Key challenges and benefits were identified, with recommendations for future research, user-centered design, technical improvements, and resource allocation.
Conclusions:
- AI implementation in health promotion and disease prevention yields positive results.
- Findings provide insights for policymakers and practitioners to optimize AI technology adoption.
- Further research and user-focused development are recommended for effective AI integration in public health strategies.
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