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Serum Laboratory Studies, Stool Test, Breath Test

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

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Updated: Sep 11, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

How Frequently Is Colorectal Cancer Recurrence Detected in a Clinic?

Gajan Srikumar^1,2, Scott J P McLaughlin^1,2, Jaxon Jebbink²

¹Department of General Surgery, Te Whatu Ora-Te Tai Tokerau, Northland, New Zealand.

Diseases of the Colon and Rectum

|August 11, 2025

Summary

Outpatient clinic follow-up rarely detects colorectal cancer recurrence, with computed tomography being the most common method. Alternative strategies for clinic follow-up should be considered due to minimal oncological benefit.

Keywords:

CEA CT Colonoscopy Colorectal cancer Detection Outpatient clinic Recurrence

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Last Updated: Sep 11, 2025

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Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

Published on: March 14, 2019

Area of Science:

Oncology
Gastroenterology
Clinical Medicine

Background:

Outpatient clinic follow-up is a long-standing practice after colorectal cancer surgery.
Evidence on the efficacy of clinic follow-up for oncological detection is limited.
Re-evaluation of clinic follow-up is necessary due to increasing patient numbers and health limitations.

Purpose of the Study:

To determine the frequency of clinical examination versus other methods in detecting colorectal cancer recurrence.
To compare the effectiveness of various detection modalities in Northland.

Main Methods:

Retrospective review of colorectal cancer recurrence detection methods.
Study period: January 2013 to December 2022 in Northland, New Zealand.
Included patients with Stage I-IV colorectal adenocarcinoma treated with curative-intent surgery.

Main Results:

Of 747 patients, 157 (21.0%) experienced recurrence.
Computed tomography (54%) was the most frequent detection method, followed by carcinoembryonic antigen (27%) and colonoscopy (6%).
Clinical examination detected only 3% of recurrences, with colonoscopy-detected recurrences showing significantly better 5-year overall survival.

Conclusions:

Outpatient clinic examination plays a minimal role in detecting colorectal cancer recurrence, especially asymptomatic cases.
The oncological benefit of routine clinic follow-up appears limited.
Resource-saving alternative strategies for post-treatment surveillance warrant consideration.