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Updated: Sep 11, 2025
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Ultrasound characteristics of cervical lymph nodes in children with infectious mononucleosis
Xinxin Bu1, Shuwen Sun2, Yanyan Zhang3
1Department of Pediatric, the First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu Province, China.
Aim:
To illustrate ultrasonographic characteristics of cervical lymph nodes in children with infectious mononucleosis (IM).
Material And Methods:
Ultrasonographic characteristics of cervical lymph nodes in 61 children with IM were retrospectively analyzed, including the location, long diameter (LD), short diameter (SD), short-to-long diameter ratio (S/L), boundary clarity, presence of lymphatic hilum, internal hyperechoic features, blood supply mode and vascular richness.
Results:
The 61 children with IM comprised 41 males and 20 females, with an average age of 7.2±3.8 years. Bilateral enlargement of cervical lymph nodes was a typical ultrasonographic manifestation of IM. Lymph node enlargement was evenly distributed on both sides of the neck. All enlarged lymph nodes were in neck zone II, with an average S/L ratio of 0.37±0.07, long diameter 33.4±6.4 mm, and short diameter 12.1±2.5 mm. Other typical ultrasonographic characteristics of cervical lymph nodes in children with IM included clear borders (100%), beads-on-a-string (98.4%), smooth edges (98.4%), visible lymphatic hila (95.1%), loose arrangement of lymphatic hila (88.5%), central blood flow signals (96.7%), and vascular richness (82.0%). Conclusions: IM children present unique ultrasonographic characteristics of cervical lymph nodes, which may assist in the early and timely diagnosis of pediatric IM in clinical practice.
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