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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

382
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
382
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

245
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
245
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

302
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
302
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

541
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
541
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

294
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
294
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

324
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
324

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Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
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Irritable Bowel Syndrome.

Katarina B Greer1, Shahnaz Sultan2

  • 1Case Western Reserve University and Cleveland Veterans Affairs Medical Center, Cleveland, Ohio (K.B.G.).

Annals of Internal Medicine
|August 11, 2025
PubMed
Summary
This summary is machine-generated.

Irritable bowel syndrome (IBS) is a common gut disorder. This article reviews new diagnostic and treatment strategies for IBS, including medications and lifestyle changes.

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Area of Science:

  • Gastroenterology
  • Internal Medicine

Background:

  • Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder affecting 4-10% of the population.
  • It is a chronic condition marked by abdominal pain, altered bowel habits, distention, or bloating.
  • IBS subtypes include IBS with constipation (IBS-C), IBS with diarrhea (IBS-D), and mixed IBS (IBS-M).

Purpose of the Study:

  • To summarize recent advancements in the diagnosis and management of IBS.
  • To discuss current and emerging pharmacologic and nonpharmacologic treatment options.
  • To highlight the importance of personalized treatment plans based on IBS subtype and symptom severity.

Main Methods:

  • Review of recent literature on IBS diagnosis and treatment.
  • Discussion of symptom-based diagnostic criteria.
  • Exploration of various therapeutic modalities including diet, lifestyle, pharmacologic, and nonpharmacologic interventions.

Main Results:

  • Diagnosis of IBS is increasingly based on symptom criteria, allowing for earlier identification.
  • Treatment strategies are becoming more personalized, tailored to specific IBS subtypes and bothersome symptoms.
  • New pharmacologic and nonpharmacologic options offer improved management for patients with IBS.

Conclusions:

  • Advances in diagnostic criteria facilitate timely IBS diagnosis.
  • Personalized treatment approaches, incorporating new therapies, are crucial for effective IBS management.
  • A combination of lifestyle modifications and targeted treatments improves patient outcomes in IBS.