Delphi-Based Global Consensus on Fuchs Endothelial Corneal Dystrophy. An Endothelial Keratoplasty Learners Group...

Area of Science:

• Ophthalmology
• Corneal Diseases
• Ocular Surface Disease

Background:

• Fuchs endothelial corneal dystrophy (FECD) is a progressive bilateral corneal disease.
• Early diagnosis and management are crucial for preserving vision and quality of life.

Purpose of the Study:

• To establish global expert consensus on the diagnosis, evaluation, and management of FECD.
• To provide recommendations for surgical interventions, including combined cataract surgery and keratoplasty.

Main Methods:

• A modified Delphi-based consensus approach was employed.
• Thirty-seven international FECD experts participated in three rounds of consensus-building.
• Consensus was defined as 70% agreement among participants.

Main Results:

• Agreement was reached on 90 out of 91 statements regarding FECD management.
• FECD is characterized by guttae and often preceded by subclinical edema.
• Descemet membrane endothelial keratoplasty is the recommended surgical treatment; no effective medical therapies exist.

Conclusions:

• Globally endorsed guidelines for FECD diagnosis and management have been established.
• These recommendations serve as a benchmark for ophthalmologists and cornea specialists.
• The consensus aims to improve patient outcomes and adapt to future advancements in FECD treatment.