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Dermatofibrosarcoma Protuberans of the Breast.
Ramita Mukherjee1, Rachana Meena2, Brijesh Kumar Singh1
1Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi.
European Journal of Breast Health
|August 12, 2025
Summary
Dermatofibrosarcoma protuberans (DFSP) is a rare breast cancer. This case highlights the importance of accurate diagnosis, as DFSP was initially misdiagnosed as a benign phyllodes tumor.
Area of Science:
- Oncology
- Surgical Pathology
- Dermatology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade, fibroblastic skin tumor.
- Breast involvement by DFSP is uncommon, accounting for 0.8-4.5% of cases.
- The standard treatment for DFSP is wide surgical excision.
Purpose of the Study:
- To report a rare case of DFSP presenting in the breast.
- To emphasize diagnostic challenges in differentiating DFSP from other breast tumors.
- To highlight the importance of histopathological confirmation.
Main Methods:
- Case report of a 42-year-old woman with a left breast mass.
- Initial diagnosis of benign phyllodes tumor.
- Histopathological analysis of wide local excision specimen.
Main Results:
- Final histopathology confirmed DFSP of the breast.
- The patient initially received an incorrect diagnosis.
- Wide local excision was performed.
Conclusions:
- DFSP of the breast is rare and can mimic other breast pathologies.
- Accurate histopathological diagnosis is crucial for appropriate management of breast DFSP.
- Prompt surgical intervention is key for managing DFSP.
