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Updated: Sep 11, 2025

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling
Published on: May 21, 2020
Role of transcriptomics in the study of oral cancer
Prabhu Manickam Natarajan1, Vidhya Rekha Umapathy2
1Department of Clinical Sciences, Center of Medical and Bio-allied Health Sciences and Research, College of Dentistry, Ajman University, Ajman, United Arab Emirates.
Abstract:
Oral cancer, a formidable public health challenge, demands innovative approaches for early detection and effective treatment. This review explores the transformative role of transcriptomics in oral cancer research, leveraging cutting-edge technologies to decode the RNA landscape of tumors. We delve into RNA sequencing (RNA-seq), single-cell RNA sequencing (scRNA-seq), long non-coding RNA sequencing (lncRNA-seq), microarray analysis, and small RNA profiling, showcasing their unique contributions to unraveling the complexities of oral cancer. By mapping gene expression patterns, identifying biomarkers, and understanding tumor heterogeneity at an unprecedented resolution, transcriptomics offers powerful insights into the molecular mechanisms driving oral cancer. Furthermore, we highlight how these approaches pave the way for personalized medicine, enabling precise therapeutic interventions and innovative treatment strategies. The review also addresses the future directions and challenges in the field, emphasizing the need for advanced computational tools and interdisciplinary collaboration to fully harness the potential of transcriptomics in transforming oral cancer care.
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