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Prevention of rhesus isoimmunization with intravenous anti-D gammaglobulin

British Journal of Obstetrics and Gynaecology
|May 1, 1977
PubMed

The prevention of rhesus isoimmunization was studied in 2247 rhesus negative mothers given varying intravenous doses of gammaglobulin (IgG) anti-D post partum. The results obtained show that 240 microgram of IgG anti-D affords excellent protection, if the efficacy of prophylaxis is monitored by a single fetal cell count at 72 hours after injection, and further doses of immunoglobulin are given in the few cases where fetal red cells remain in the circulation.

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