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Updated: Sep 11, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
RevCore thrombectomy device effectively restores venous stent patency by treating iliofemoral caval in-stent
Taimur Saleem1, Seshadri Raju1
1The RANE Center for Venous and Lymphatic Diseases, Jackson, MS.
Insights
The RevCore mechanical thrombectomy device effectively treated symptomatic in-stent restenosis in iliofemoral venous stents. This minimally invasive procedure showed high success rates with rapid patient recovery and minimal complications.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Medical Devices
Background:
- Symptomatic in-stent restenosis (ISR) in iliofemoral caval venous stents poses a significant clinical challenge.
- Accurate differentiation between ISR and stent compression is crucial for effective treatment planning.
Purpose of the Study:
- To describe the experience and outcomes of using the RevCore mechanical thrombectomy device for treating symptomatic ISR in iliofemoral caval venous stents.
- To evaluate the safety and efficacy of the RevCore device in this patient cohort.
Main Methods:
- A series of 40 patients with symptomatic ISR in iliofemoral caval venous stents were treated with the RevCore device.
- Preoperative computed tomography venography was used to distinguish ISR from stent compression.
- Intravascular ultrasound was utilized for procedural assessment of ISR resolution.
Main Results:
- All 40 patients achieved ≥50% ISR resolution post-procedure.
- Complete symptom resolution was observed in all patients.
- The procedure was minimally invasive with low blood loss (<10 mL) and short operative time (<30 minutes).
- No perioperative pulmonary embolism occurred, and only one patient (2.5%) required reintervention during follow-up (2-24 months).
Conclusions:
- The RevCore mechanical thrombectomy device is a safe and effective option for treating symptomatic ISR in iliofemoral caval venous stents.
- The device facilitates a minimally invasive approach with excellent clinical outcomes and a low reintervention rate.
Abstract:
Experience with the RevCore mechanical thrombectomy device in a series of 40 patients is described. The device was employed in the treatment of symptomatic in-stent restenosis (ISR) in iliofemoral caval venous stents in these patients. Computed tomography venography was performed preoperatively to differentiate ISR from stent compression in all patients who underwent intervention. All patients were treated in a single session with a mean estimated blood loss of <10 mL with an average operative time of <30 minutes. Alteplase was not used in any patient. All patients were discharged home the same day. Resolution of ≥50% ISR at the end of the procedure on intravascular ultrasound examination was noted in all patients. Symptom resolution was noted in all patients after the use of the RevCore device. No clinical perioperative pulmonary embolism was observed. Only one patient (2.5%) required reintervention during the follow-up period (range, 2-24 months).
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