Related Experiment Video
Updated: Sep 11, 2025

10:19
Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
25.7K
Prolonged and Recurrent De Quervain's Thyroiditis After Thyroid Fine Needle Aspiration
Kyrstin Lane1, Brendan Pelikh2, Jianyu Rao3
1Endocrinology, Diabetes and Metabolism, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, USA.
Cureus
|August 12, 2025
Summary
De Quervain's thyroiditis, a self-limited thyroid inflammation, can be complicated by fine needle aspiration (FNA). This case suggests avoiding FNA in suspected De Quervain's thyroiditis to prevent prolonged inflammation.
Area of Science:
- Endocrinology
- Pathology
Background:
- De Quervain's thyroiditis (subacute thyroiditis) is a transient inflammatory condition of the thyroid gland.
- Diagnosis relies on clinical presentation, physical exam, laboratory tests, and imaging, with fine needle aspiration (FNA) generally reserved for unclear cases or suspicion of malignancy.
Observation:
- A 75-year-old male presented with symptoms consistent with De Quervain's thyroiditis and an inflammatory thyroid nodule.
- Thyroid fine needle aspiration (FNA) was performed for further evaluation of the nodule.
- The patient experienced a prolonged clinical course following the FNA, presumed to be due to exacerbated thyroid inflammation.
Findings:
- Thyroid fine needle aspiration (FNA) may potentially worsen inflammation in cases of De Quervain's thyroiditis.
- Distinguishing De Quervain's thyroiditis from other causes of thyroid pain is crucial for appropriate management.
Implications:
- This case underscores the importance of accurate diagnosis to avoid potentially detrimental procedures like FNA in subacute thyroiditis.
- Serial thyroid ultrasounds may be a valuable tool to monitor disease progression and potentially obviate the need for FNA, thereby preventing complications.
Related Concept Videos
The Thyroid Gland
4.3K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.3K
Myasthenia Gravis: Diagnostic Tests
1.3K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
1.3K
Myasthenia Gravis: Overview and Treatment
1.9K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.9K

