Penile calciphylaxis

Calciphylaxis is a rare, highly mortal disease, typically diagnosed in patients with end-stage renal disease. This disorder usually presents as necrotic ulcers in acral or adipose areas. Penile necrosis due to calciphylaxis is an uncommon condition with a poor prognosis. Few cases have been described in the literature. We present the case of a 45-year-old male with a history of type 2 diabetes and chronic renal failure on dialysis, who developed painful necrotic ulcers on the glans, had altered phosphocalcic metabolism, and was found to have calcium deposits on imaging studies. Treatment with intravenous sodium thiosulfate was initiated, resulting in favorable evolution.