Intrapulmonary Epstein-Barr Virus-Associated Smooth Muscle Tumor after Bilateral Lung Transplantation: A Case Report

Epstein-Barr virus-associated smooth-muscle tumor is an uncommon oncovirus-related neoplasm in the setting of solid organ transplantation. We report a case of a 69-year-old man who had no symptoms and a lung nodule was found incidentally on chest CT 2 years after bilateral lung transplantation. Surgical resection of the nodule was performed and pathology proved an EBV-SMT. No evidence of recurrence or metastasis was found till now. An incidental solid lung nodule with interval growth in the late stage of lung transplant should raise the suspicion of EBV-SMT. The surgery resection is the treatment of choice with a favorable prognosis.