Related Experiment Video
Updated: Sep 11, 2025

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
[Vanek's tumor as an uncommon cause of digestive bleeding]
Sergio Morínigo1, Maisa Vallejos1, Sebastián Díaz Duba1
1Departamento de Gastroenterología y Endoscopía Digestiva, Hospital de Clínicas, San Lorenzo, Paraguay.
Abstract:
Gastrointestinal tract polyps exhibit a wide range of characteristics, from benign to potentially malignant lesions. Vanek's polyp, a rare entity, is characterized by its inflammatory infiltrate and vascular alterations, often leading to confusion with adenomatous lesions. We present the case of a 77-year-old woman with a one-month history of rectal bleeding, requiring hospitalization during one of the episodes. Colonoscopy revealed a pedunculated polyp, which was resected without complications. Histopathological analysis showed a lymphoplasmacytic infiltrate, multiple vessels with fibrinoid necrosis, and no neoplastic atypia. Due to the nonspecific nature of the report, immunohistochemical studies were performed, revealing CD34 positivity in the vessels and vimentin positivity in mesenchymal cells. These findings suggest a differential diagnosis from inflammatory fibroid polyps. Vanek's polyps are uncommon lesions that require accurate diagnosis and appropriate management. Recent trends show an increase in the identification of these polyps, likely due to advancements in diagnostic techniques.
Insights
Vanek's polyp, a rare gastrointestinal lesion, presents with inflammation and vascular changes, mimicking adenomas. Accurate diagnosis is crucial for appropriate management of this uncommon finding.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Gastrointestinal polyps range from benign to malignant.
- Vanek's polyp is a rare inflammatory lesion often misdiagnosed as adenomatous.
Observation:
- A 77-year-old woman presented with rectal bleeding due to a pedunculated polyp.
- Colonoscopy revealed and resected the polyp.
- Histopathology showed lymphoplasmacytic infiltrate and vascular changes without atypia.
Findings:
- Immunohistochemistry revealed CD34+ vessels and vimentin+ mesenchymal cells.
- These findings aid in differentiating Vanek's polyp from inflammatory fibroid polyps.
Implications:
- Accurate diagnosis of Vanek's polyp is essential for patient management.
- Increased identification of Vanek's polyps may be linked to improved diagnostic techniques.
Related Concept Videos
Esophageal Varices-I: Introduction
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Blood Supply to the Digestive System
Blood Supply to the Digestive System: The splanchnic circulation involves three main arteries: the celiac artery (also known as the celiac trunk) and the superior and inferior mesenteric...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
