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Updated: Sep 11, 2025

Label-free Single Molecule Detection Using Microtoroid Optical Resonators
Published on: December 29, 2015
Terahertz asynchronous optical sampling spectroscopy with lock-in detection
Abstract:
We demonstrate a terahertz asynchronous optical sampling (THz-ASOPS) spectrometer incorporating a lock-in amplifier. The experimental setup employs a high-voltage pulse generator to drive a photoconductive antenna emitter, generating precisely modulated terahertz pulses that are subsequently detected by a photoconductive antenna detector. The detection system features a two-stage amplification process: initial signal amplification through a low-noise current preamplifier, followed by processing with a digital lock-in amplifier. Experimental characterization demonstrates significant performance enhancements, with a 3-fold improvement in the time-domain peak signal-to-noise ratio and a 5 dB increase in the spectral dynamic range. These results substantiate the effectiveness of the lock-in detection approach in enhancing THz-ASOPS spectroscopic performance.

