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Related Concept Videos

Overview of Electron Microscopy01:25

Overview of Electron Microscopy

The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.

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Related Experiment Video

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Fluorescence detection methods for microfluidic droplet platforms
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Capillary fiber-based optical machine gun for micro particle continuous shooting.

Jiahao Du, Tingting Yuan, Xiaotong Zhang

    Optics Express
    |August 13, 2025
    PubMed
    Summary

    Researchers developed an optical machine gun using annular-core capillary fiber for directional particle emission. This device enables precise control over particle movement, showing potential for microfluidic applications and targeted drug delivery.

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    Area of Science:

    • Optics and Photonics
    • Microfluidics
    • Biomedical Engineering

    Background:

    • Traditional particle manipulation methods often lack precise directional control.
    • Continuous and guided particle emission is crucial for advanced microfluidic applications.

    Purpose of the Study:

    • To propose and demonstrate an optical machine gun based on annular-core capillary fiber for directional particle emission.
    • To investigate the influence of optical power and fluid injection pressure on particle velocity and trajectory.

    Main Methods:

    • Fabrication of an optical device using an annular-core capillary fiber with a 12° cone structure.
    • Illumination of the fiber core to create a cone-shell light field for particle guidance.
    • Systematic variation of fluid injection pressure and optical power to study particle dynamics.

    Main Results:

    • Particle velocity increases with output optical power at a constant injection pressure.
    • Particle injection pressure has minimal effect on particle velocity when optical power is constant.
    • Demonstrated linear particle motion at 150 mW output power, contrasting with divergent motion at 0 mW.

    Conclusions:

    • The developed optical machine gun achieves continuous, directional particle emission.
    • The device shows significant potential for cell manipulation in microfluidic systems and targeted drug delivery.