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Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Related Experiment Video

Updated: Sep 11, 2025

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Progressive pulmonary fibrosis: current perspectives in diagnostic imaging.

Prerana Agarwal1, Christopher L Schlett1, Fabian Bamberg1

  • 1Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg im Breisgau, Germany.

BJR Open
|August 13, 2025
PubMed
Summary

Some patients with interstitial lung diseases (ILDs) show disease progression despite treatment. High-resolution computed tomography (HRCT) helps identify high-risk patients and monitor disease, with new AI methods emerging.

Keywords:
hypersensitivity pneumonitisinterstitial lung diseasesmultidetector computed tomographypulmonary fibrosissarcoidosis

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Area of Science:

  • Pulmonology
  • Radiology
  • Medical Imaging

Background:

  • A subset of patients with interstitial lung diseases (ILDs) experience progressive disease despite standard treatments.
  • This progression, termed progressive fibrosing ILD, mirrors idiopathic pulmonary fibrosis and leads to worsening symptoms, declining lung function, and reduced survival.
  • Radiological imaging is crucial for ILD diagnosis and management within multidisciplinary ILD boards.

Purpose of the Study:

  • To highlight the role of high-resolution computed tomography (HRCT) in identifying patients with progressive fibrosing ILDs.
  • To emphasize the importance of HRCT in assessing disease progression and providing prognostic insights.
  • To introduce emerging quantitative imaging techniques, including machine learning, for ILD evaluation.

Main Methods:

  • Review of the role of radiological imaging, specifically HRCT, in the diagnosis and monitoring of ILDs.
  • Discussion of visual assessment methods for evaluating disease advancement on HRCT.
  • Introduction of emerging quantitative imaging techniques and machine learning applications in ILD progression assessment.

Main Results:

  • HRCT is instrumental in diagnosing ILDs and plays a critical role in multidisciplinary ILD boards.
  • HRCT aids in identifying patients at higher risk for disease progression and offers prognostic value.
  • Serial HRCT imaging is essential for tracking disease progression over time.

Conclusions:

  • HRCT is a vital tool for managing progressive fibrosing ILDs, aiding in risk stratification and prognosis.
  • Visual assessment of HRCT remains the primary method for evaluating disease progression.
  • Quantitative imaging techniques, including machine learning, show promise for future ILD assessment and require further validation.