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Unmasking Plummer-Vinson Syndrome: A Rare Case Report
B Radhika1, Aswini Sekar2, Priyanka Gandhi3
1Associate Professor, Department of Periodontics, Chettinad Dental College and Research Institute, Kancheepuram, India.
Contemporary Clinical Dentistry
|August 13, 2025
Summary
Plummer-Vinson syndrome (PVS), a rare condition in men, presents with anemia, esophageal strictures, and dysphagia. Early diagnosis and iron repletion are key for managing this precancerous disorder.
Area of Science:
- Gastroenterology
- Hematology
- Otorhinolaryngology
Background:
- Plummer-Vinson syndrome (PVS), also known as Paterson Brown-Kelly Syndrome, is characterized by a triad of microcytic hypochromic anemia, esophageal strictures, and dysphagia.
- PVS predominantly affects middle-aged women and is rarely documented in males, making this case report unique.
Observation:
- A 49-year-old female presented with classic symptoms indicative of Plummer-Vinson syndrome.
- The patient's presentation highlighted the typical triad of symptoms associated with PVS.
Findings:
- Plummer-Vinson syndrome is recognized as a precancerous condition with a significant risk of malignant transformation.
- Early detection and intervention are critical for improving patient prognosis and preventing complications.
Implications:
- Surveillance endoscopy and barium swallow tests are recommended for ongoing monitoring of PVS patients.
- Treatment strategies include iron repletion to address anemia and dysphagia, and esophageal dilatation for symptomatic relief.
- This case underscores the importance of considering systemic conditions like PVS in dental practice and the interconnectedness of oral and systemic health, particularly in underserved populations.
