Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Longitudinal Studies01:26

Longitudinal Studies

247
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
247
Longitudinal Research02:20

Longitudinal Research

12.5K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.5K
Relationship Formation02:12

Relationship Formation

41.0K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
41.0K
Aging01:26

Aging

182
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
182
Dimensions of Health and Illness01:21

Dimensions of Health and Illness

8.2K
The factors influencing the health-illness continuum can be internal or external and may or may not be under conscious control. They are related to the following eight human dimensions, and each dimension is interrelated to one other.
8.2K
Models of Health Promotion and Illness Prevention II01:18

Models of Health Promotion and Illness Prevention II

1.7K
The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A bibliometric analysis of Neuropsychology's published corpus (1987-2024): How has the science evolved, and does study content impact citation rates?

Neuropsychology·2026
Same author

Examining the additive risk of TBI and comorbid conditions on dementia in military veterans: a retrospective cohort study.

Alzheimer's research & therapy·2026
Same author

Cognitive function in immigrants from Mexico and Latin America: The role of age at migration.

Journal of Alzheimer's disease : JAD·2026
Same author

Differential associations between traumatic brain injury severity and four dementia phenotypes in military veterans.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Life course neighborhood conditions and change: a 20-year examination of neighborhood context and associations with Alzheimer's disease biomarkers in late life.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Precision medicine for Alzheimer's disease in Down syndrome.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Related Experiment Video

Updated: Sep 11, 2025

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.5K

Health and Aging Brain Study-Health Disparities (HABS-HD) methods and partner characteristics.

Melissa E Petersen1,2, Zhengyang Zhou3, James R Hall1,2

  • 1Institute for Translational Research University of North Texas Health Science Center Fort Worth Texas USA.

Alzheimer'S & Dementia (New York, N. Y.)
|August 13, 2025
PubMed
Summary

The Health and Aging Brain Study-Health Disparities (HABS-HD) reveals significant differences in brain health across racial/ethnic groups. These disparities in cognition, biomarkers, and social factors are crucial for understanding aging and related diseases.

Keywords:
Alzheimer's diseaseHispanicamyloid/tau/neurodegenerationbiomarkersnon‐Hispanic Black

More Related Videos

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

7.4K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.1K

Related Experiment Videos

Last Updated: Sep 11, 2025

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.5K
Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

7.4K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.1K

Area of Science:

  • Neuroscience
  • Gerontology
  • Public Health

Background:

  • The Health and Aging Brain Study-Health Disparities (HABS-HD) is an ongoing prospective study investigating brain health and aging.
  • This work describes the cohort's baseline characteristics and study methodology.

Purpose of the Study:

  • To characterize the baseline demographics, medical history, cognitive status, and biological markers of a diverse HABS-HD cohort.
  • To identify disparities in brain aging across non-Hispanic Black (NHB), Hispanic, and non-Hispanic White (NHW) participants.

Main Methods:

  • Analysis of data from 1066 NHB, 1425 Hispanic, and 1349 NHW participants in the HABS-HD study.
  • Descriptive statistics for demographic, medical, and diagnostic characteristics.
  • Examination of differences in amyloid (A), tau (T), and neurodegeneration (N) biomarkers (proteomic and neuroimaging), cognitive performance, and social determinants of health (SDoH).

Main Results:

  • Significant group differences observed in age, education, sex, and cognitive diagnosis.
  • Higher rates of cognitive impairment (MCI, dementia), hypertension, and diabetes in NHB and Hispanic participants compared to NHW.
  • Differences in plasma (A/T[N]) biomarkers, neuroimaging measures (white matter hyperintensities), and positron emission tomography amyloid positivity rates (lower in NHB vs. NHW).
  • Group differences also noted in SDoH factors (income, insurance, healthcare access) and cognitive test performance.

Conclusions:

  • Baseline HABS-HD cohort characteristics reveal significant demographic, medical, cognitive, and biological disparities across racial/ethnic groups.
  • These identified differences in A/T[N] biomarkers and SDoH are critical for understanding aging and age-related diseases.
  • The findings highlight the importance of addressing health disparities in brain aging research.