Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functional Brain Systems: Reticular Formation01:13

Functional Brain Systems: Reticular Formation

2.6K
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
2.6K
Organization of the Brain01:30

Organization of the Brain

1.2K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
1.2K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

915
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
915
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

3.9K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
3.9K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

4.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.6K
Diencephalon: Anatomical Regions01:30

Diencephalon: Anatomical Regions

2.9K
The diencephalon, etymologically translated as 'through brain,' plays an integral role as the conduit between the cerebrum and the vast extent of the nervous system. However, the olfactory system is an exception, as it interfaces directly with the cerebrum. The diencephalon, deeply ensconced beneath the cerebrum, primarily consists of three paired structures — the thalamus, hypothalamus, and epithelamus. It also includes accessory structures such as the subthalamus, which houses the...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

JAMA·2026
Same author

Wanting this, not that: The neural circuit that turns specific expectations into actions.

PLoS biology·2026
Same author

Functional network contributions to longitudinal tau spread in Posterior Cortical Atrophy.

NPJ dementia·2026
Same author

Optimising a behavioural intervention to support endocrine therapy adherence for women with breast cancer: protocol for the ROSETA optimisation factorial randomised controlled trial.

Trials·2026
Same author

Survival in node-positive early oral squamous cell carcinoma following sentinel lymph node biopsy or elective neck dissection.

Oral oncology·2026
Same author

Rhesus macaques with an <i>OPA1</i> mutation demonstrate features of autosomal dominant optic atrophy.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Sep 11, 2025

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

8.4K

Intrinsic functional and structural network organization in the macaque insula.

Joey A Charbonneau1,2, Erika P Raven3, Yuta Katsumi4

  • 1Neuroscience Graduate Program, University of California Davis, Davis, CA, United States.

Imaging Neuroscience (Cambridge, Mass.)
|August 13, 2025
PubMed
Summary

This study bridges the human-macaque research gap using advanced in vivo MRI to map the macaque insula. Findings show clear correspondence with human brain studies, supporting the macaque model for neuroscience research.

Keywords:
comparativediffusionfunctional connectivityinsulainteroceptionmonkey

More Related Videos

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

8.5K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

5.1K

Related Experiment Videos

Last Updated: Sep 11, 2025

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

8.4K
Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

8.5K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

5.1K

Area of Science:

  • Neuroscience
  • Primate Research
  • Medical Imaging

Background:

  • In vivo magnetic resonance imaging (MRI) offers insights into human brain structure and function.
  • Limitations in resolution and correlational nature necessitate animal models for detailed neuroanatomy and causal manipulation.
  • A translational gap exists between human MRI studies and animal model research.

Purpose of the Study:

  • To bridge the translational gap between human and animal model neuroscience research.
  • To conduct a detailed, multimodal in vivo investigation of the macaque insula.
  • To establish the macaque as a suitable model for studying the insula.

Main Methods:

  • Utilized functional MRI (fMRI) and diffusion MRI (dMRI) in macaques.
  • Applied analysis methods and imaging modalities available for human use.
  • Correlated findings with existing human in vivo MRI and primate postmortem studies.

Main Results:

  • Demonstrated a neural architecture in the macaque insula with clear correspondence to human in vivo MRI findings.
  • Convergent results across multiple analysis methods and imaging modalities.
  • Established clear links between in vivo macaque insula data and postmortem studies.

Conclusions:

  • The macaque insula exhibits a neural architecture highly comparable to humans.
  • The study supports the translational potential of the macaque model for in vivo brain research.
  • Multimodal MRI approaches in macaques enhance understanding of insula neuroanatomy and function.