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Related Concept Videos

Lateralization01:28

Lateralization

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Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
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Cerebral Hemispheres01:05

Cerebral Hemispheres

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The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
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Higher Mental Functions of the Brain: Language01:10

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Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
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Lobes of the Cerebrum01:22

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The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
Frontal lobe
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Functional Brain Systems: Limbic System01:15

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The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
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Neuroplasticity01:01

Neuroplasticity

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Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
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Related Experiment Video

Updated: Sep 11, 2025

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
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Evidence for a compensatory relationship between left- and right-lateralized brain networks.

Madeline Peterson1, Rodrigo M Braga2, Dorothea L Floris3,4

  • 1Department of Psychology, Brigham Young University, Provo, UT, United States.

Imaging Neuroscience (Cambridge, Mass.)
|August 13, 2025
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Brain hemispheres show functional asymmetry. This study reveals a dependent relationship between left- and right-lateralized brain networks, impacting conditions like autism and schizophrenia.

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Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Brain Imaging

Background:

  • Human brain hemispheres exhibit functional asymmetry, with language networks typically lateralized to the left.
  • The degree of lateralization in other functional networks and their interdependencies remains largely unexplored.
  • Understanding network lateralization is crucial for insights into neurodevelopmental disorders.

Purpose of the Study:

  • To quantify lateralization across 17 functional brain networks using relative cerebral hemisphere surface area.
  • To test if language, visuospatial attention, and executive control networks show the greatest lateralization.
  • To investigate the dependent relationship between the lateralization of different functional networks within individuals.

Main Methods:

  • Quantified network lateralization by measuring relative left and right cerebral hemisphere surface area.
  • Examined the validity and reliability of the surface area-based lateralization measure.
  • Utilized correlation matrices and factor analyses across multiple large-scale neuroimaging datasets (HCP, HCP-D, NSD).

Main Results:

  • Confirmed significant left lateralization for the language network and significant right lateralization for attention and executive control networks.
  • Found evidence supporting a dependent relationship: greater left lateralization in one network correlated with greater right lateralization in another, systematically across individuals.
  • Identified specific networks, including language, attention, and executive control, as demonstrating significant lateralization.

Conclusions:

  • Brain functional networks exhibit varying degrees of lateralization, with language, attention, and executive control networks showing notable asymmetry.
  • A systematic, dependent relationship exists between the lateralization patterns of different functional networks within individuals.
  • These findings enhance understanding of macro-scale brain organization and have implications for neurodevelopmental conditions characterized by lateralization disruptions.