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Updated: Sep 11, 2025
Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells
Published on: November 17, 2017
Treatment of chronic wounds with cold plasma: a randomised, single-blind, placebo-controlled clinical study
Robert Strohal1, Martina Mittlböck2, Lisa Gebhardt3
1Department of Dermatology, Federal Academic Teaching Hospital Feldkirch, Feldkirch, Austria.
Objective:
This study aimed to investigate the wound healing properties of cold atmospheric plasma (CAP) in patients with chronic wounds.
Method:
This was a prospective, multicentre, two-arm, randomised, single-blind clinical study which compared the wound healing treatment of CAP with placebo, both of which were combined with best practice wound care.
Results:
The study cohort consisted of 70 patients: 35 in the CAP group and 35 in the placebo group. There was a statistically significant (p<0.0001) reduction in the wound area at the end of the study, and faster wound healing, with the use of CAP compared with a placebo device.
Conclusion:
The results of this study showed that without requiring adjunctive therapies, the CAP device represents a safe, well-tolerated, and highly effective therapeutic option for wounds in that it promotes their rapid healing.
