Related Experiment Video
Updated: Sep 11, 2025
11:12
Immunometabolic Circuits in Infection for Advancing Host Directed Therapies
Published on: September 13, 2024
531
Synbiotics: An Emerging Frontier in Infectious Diseases Control
Nikita Jangra1, Nikita Chahar1, Aparna Parmar2
1Medical Microbiology and Bioprocess Technology Laboratory, Department of Microbiology, Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Probiotics and Antimicrobial Proteins
|August 13, 2025
Summary
Synbiotics, a blend of prebiotics and probiotics, help restore gut balance and manage infectious diseases. They offer a promising alternative or supplement to antibiotics by fighting pathogens and supporting immune health.
Area of Science:
- Microbiology
- Immunology
- Gastroenterology
Background:
- The human gut microbiome plays a vital role in health, influencing digestion, nutrient absorption, and immunity.
- Gut microbiota dysbiosis is linked to infectious disease development.
- Synbiotics (prebiotics + probiotics) are increasingly used for immune and gastrointestinal health.
Purpose of the Study:
- To explore the potential of synbiotics as alternatives or adjuncts to antibiotics for infectious diseases.
- To detail available synbiotic formulations and their mechanisms of action.
- To address challenges and recent advancements in synbiotic efficacy.
Main Methods:
- Review of scientific literature on synbiotics and infectious diseases.
- Analysis of synbiotic formulations and their clinical applications.
- Discussion of mechanisms by which synbiotics antagonize pathogens.
Main Results:
- Synbiotics effectively restore gut eubiosis and modulate the microbiome.
- Dietary synbiotics show promise in treating infections like hepatitis, gastroenteritis, and sepsis.
- Synbiotics combat pathogens by maintaining homeostasis, competing for resources, producing antimicrobials, and stimulating immunity.
Conclusions:
- Synbiotics are potent in managing infectious diseases by restoring gut microbiota homeostasis.
- They offer a viable alternative or adjunct to antibiotic therapy.
- Ongoing research aims to enhance synbiotic efficacy through novel approaches.
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