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Regulation of Stroke Volume

Regulation of Stroke Volume

The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...

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Related Experiment Video

Updated: Sep 11, 2025

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

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Published on: August 18, 2015

Salt Substitution and Recurrent Stroke and Death-Reply

Xiong Ding^1,2, Maoyi Tian^3,4, Lijing L Yan^1,2

¹School of Public Health, Wuhan University, Wuhan, China.

JAMA Cardiology

|August 13, 2025

Summary

No abstract available in PubMed .

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