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Autoimmune Hemolytic Anemia with Autoimmune Hypothyroidism: A Case Report
Prakriti Karki1, Parikshit Prasai2, Vivek Acharya Chetri3
1B.P. Koirala Institute of Health Science, Ghopa, Dharan, Nepal.
JNMA; Journal of the Nepal Medical Association
|August 13, 2025
Summary
Hashimoto's thyroiditis can rarely occur with autoimmune hemolytic anemia. This case highlights the importance of considering hemolytic anemia in Hashimoto's patients, guiding physician management.
Area of Science:
- Endocrinology
- Hematology
- Immunology
Background:
- Autoimmune hemolytic anemia (AIHA) involves autoantibodies attacking red blood cells, a rare condition.
- Autoimmune thyroid disease, like Hashimoto's thyroiditis, is often linked with other autoimmune disorders.
- Co-occurrence of Hashimoto's thyroiditis and AIHA is infrequently documented.
Observation:
- A 22-year-old woman with known Hashimoto's thyroiditis presented with serum antibodies against red blood cells.
- Blood investigations confirmed findings indicative of hemolytic anemia.
Findings:
- The patient was diagnosed with concurrent Hashimoto's thyroiditis and autoimmune hemolytic anemia.
- Treatment involved blood transfusion, thyroxine, and steroid therapy.
Implications:
- This case underscores the need for physicians to suspect AIHA in patients diagnosed with Hashimoto's thyroiditis.
- Early diagnosis and management of AIHA can improve outcomes for patients with coexisting autoimmune conditions.
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