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Health Benefits of Phytosterols in the Management of Several Non-Communicable Disorders
Amany S Aboutaleb1, Eman S Mahdy2, Sara M Khamies2
1Pharmacology and Toxicology Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Abstract:
Phytosterols, encompassing plant sterols and stanols, are bioactive compounds prevalent in plant-derived foods. These compounds have garnered attention for their extensive pharmacological properties, which include cardioprotective, anticancer, neuroprotective, hepatoprotective, wound healing, antidiabetic, antimicrobial, immunomodulatory, and anti-aging effects, as well as potential applications in managing ocular diseases and hormonal disturbances. Recent studies indicate that phytosterols may significantly reduce lipid profiles, thereby mitigating cardiovascular disease risk. Furthermore, their role in cancer prevention is underscored by evidence suggesting a significant reduction in cancer risk associated with phytosterol-rich diets. This review aims to gather the current literature on the therapeutic potential of phytosterols for human health, highlighting their diverse biological activities. Overall, this comprehensive overview seeks to elucidate the promising role of phytosterols in enhancing health outcomes and their viability as therapeutic agents.
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