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Updated: Sep 11, 2025

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents
Published on: November 1, 2019
Optimization-based dietary recommendations for healthy eating
Xu-Wen Wang1, Scott T Weiss1, Frank B Hu1,2,3
1Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Abstract:
Various diet scores have been developed to assess compliance with dietary guidelines. Yet, enhancing those diet scores is very challenging. Here, we tackle this issue by formalizing an optimization problem and solving it with simulated annealing. Our optimization-based dietary recommendation (ODR) approach, evaluated using Diet-Microbiome Association study data, provides efficient and reasonable recommendations for different diet scores. ODR has the potential to enhance nutritional counseling and promote dietary adherence for healthy eating.
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