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Related Experiment Videos

[Experimental cholera in the monkey].

B Ivanoff, G Nis, D Robert

    Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences. Serie D: Sciences Naturelles
    |June 13, 1977
    PubMed
    Summary
    This summary is machine-generated.

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    Cotton-top marmosets, but not baboons or rhesus monkeys, can contract a typical cholera disease. This finding is crucial for developing effective cholera models in non-human primates.

    Area of Science:

    • Primate models
    • Infectious disease research
    • Microbiology

    Context:

    • Previous research utilized baboons (Papio, P. anubis) and rhesus monkeys for cholera studies.
    • These established models yielded unfavorable results for studying cholera.

    Purpose:

    • To identify a suitable primate model for experimental cholera studies.
    • To investigate the susceptibility of different primate species to cholera.

    Summary:

    • Experimental cholera induction was attempted in baboons, rhesus monkeys, and cotton-top marmosets.
    • A typical cholera disease was successfully established in cotton-top marmosets (Saguinus oedipus).
    • Baboons and rhesus monkeys did not develop a typical cholera disease.

    Impact:

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    • The cotton-top marmoset serves as a viable new primate model for cholera research.
    • Facilitates further investigation into cholera pathogenesis and treatment strategies.
    • Advances the understanding of host-pathogen interactions in primate models.