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Updated: Sep 11, 2025
08:46
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
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Fertility Preservation for Transgender and Gender-diverse Individuals: Current Practices and Future Directions
Alexandra Minnihan1, Dana Baraki2, Mindy S Christianson2,3
1Department of Obstetrics and Gynecology, University of Florida, Gainesville, Florida.
Clinical Obstetrics and Gynecology
|August 14, 2025
Summary
Transgender individuals should discuss fertility preservation options before starting gender-affirming care. Options vary by gender identity, including cryopreservation of eggs, sperm, or ovarian/testicular tissue.
Area of Science:
- Reproductive Endocrinology
- Transgender Health
Background:
- Gender-affirming care, including hormone therapy and surgery, can impact reproductive capacity.
- Fertility preservation is a crucial consideration for transgender individuals before commencing treatment.
Purpose of the Study:
- To outline recommended fertility preservation counseling for transgender individuals.
- To detail available fertility preservation options based on gender identity and age.
Main Methods:
- Review of current medical literature and clinical guidelines on fertility preservation in transgender populations.
- Analysis of established and experimental cryopreservation techniques.
Main Results:
- Fertility preservation counseling is recommended prior to initiating gender-affirming interventions.
- Options for transgender males include embryo, oocyte, and ovarian tissue cryopreservation.
- Sperm cryopreservation is available for transgender females; testicular tissue cryopreservation is experimental for prepubertal males.
Conclusions:
- Informed decision-making regarding fertility preservation is essential for transgender individuals.
- A range of cryopreservation options exist, tailored to individual needs and circumstances.
- Continued research into experimental techniques like testicular tissue cryopreservation is warranted.
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