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Multiple Sclerosis: Enhancing Botulinum Toxin Effects in Spasticity Management, a Systematic Review

Daniela Poenaru1, Miruna Ioana Sandulescu1, Catalin Furculescu2

  • 1Rehabilitation Department, Carol Davila University of Medicine, 050474 Bucharest, Romania.

Journal of Clinical Medicine
|August 14, 2025
PubMed
Summary

This review explores ways to improve botulinum toxin (BoNT) effectiveness for multiple sclerosis (MS) spasticity. Current research on adjunctive therapies like electrical stimulation and exercise in MS patients is limited, indicating a need for more studies.

Keywords:
botulinum toxinmultiple sclerosisspasticity

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