Cannabis for female orgasmic disorder/difficulty: a systematic review.

Area of Science:

• Sexuality and Reproductive Health
• Pharmacology
• Women's Health

Background:

• Female orgasmic disorder/difficulty (FOD/difficulty) affects a significant portion of women globally.
• Conventional treatments for FOD/difficulty are lacking.
• Cannabis is increasingly explored as a potential therapeutic option.

Purpose of the Study:

• To systematically review the existing literature on cannabis and its effects on female orgasm function.
• To evaluate the impact of cannabis on women with and without FOD/difficulty.

Main Methods:

• Systematic review following PRISMA guidelines.
• Searches across major databases (PubMed, Google Scholar, Cochrane, Embase).
• Inclusion of 1 randomized controlled trial and 15 observational studies.

Main Results:

• Nine studies using cannabis before sexual activity reported improvements in orgasm frequency, ease, intensity, quality, and/or multiorgasmic capacity.
• Two studies on general cannabis use showed mixed results, with one noting improved orgasm and reduced dysfunction with more frequent use.
• Some studies reported negative effects, including situational anorgasmia and difficulty with focus.

Conclusions:

• Cannabis demonstrates potential as a treatment for FOD/difficulty.
• Further high-quality randomized controlled trials are necessary to determine optimal dosing, administration, and strain specificity.
• Medical cannabis may warrant consideration as a first-line treatment for FOD/difficulty.