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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Related Experiment Video

Updated: Sep 11, 2025

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
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When stroke hides: A case of negative diffusion MRI.

Kenza Berrada1, Ibtissam El Ouali2, Salma El Aouadi2

  • 1Department of Neuroradiology. Specialties Hospital, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.

Radiology Case Reports
|August 14, 2025
PubMed
Summary

This case highlights rare ischemic strokes missed by initial MRI diffusion-weighted imaging (DWI). Multimodal imaging and repeat MRI are crucial for diagnosing stroke when clinical suspicion is high.

Keywords:
IschemiaMRINegative-diffusionStroke

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Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Ischemic stroke diagnosis often relies on MRI diffusion-weighted imaging (DWI).
  • Some stroke cases present atypically, lacking typical DWI findings, creating diagnostic challenges.

Observation:

  • A 75-year-old woman with hypertension and diabetes presented with left-sided weakness and facial asymmetry.
  • Initial brain MRI with DWI was normal, but subsequent ASL imaging showed reduced right hemisphere perfusion.

Findings:

  • MR angiography revealed a right internal carotid artery occlusion.
  • Follow-up imaging confirmed a large right-sided ischemic infarct.

Implications:

  • This case emphasizes the diagnostic value of multimodal neuroimaging in stroke evaluation.
  • Repeating MRI is vital when clinical suspicion for stroke persists despite a normal initial DWI scan.