Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

409
Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
409
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

118
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
118
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

6.0K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
6.0K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

3.3K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
3.3K
Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

Dysrhythmias VII: Nursing Management of Dysrhythmias

107
Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
107
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

107
Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
107

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Novel KCNJ2 p.Glu299Ala Variant Associated with Short QT Phenotype and Persistent Atrial Fibrillation in a Child.

Life (Basel, Switzerland)·2026
Same author

Ataxia-Telangiectasia and Associated Bronchiectasis: Case Report and Literature Review.

Journal of clinical medicine·2026
Same author

Genetic Variants of Thymic Stromal Lymphopoietin and Non-IgE-Mediated Food Allergy.

International journal of molecular sciences·2026
Same author

Intravenous Immunoglobulin Efficacy and Safety in Paediatric Patients Diagnosed with Acute Myocarditis.

Journal of clinical medicine·2025
Same author

Refining Patient Selection Criteria for LV-Only Fusion Pacing in Cardiac Resynchronization Therapy: A Systematic Review.

Journal of clinical medicine·2025
Same author

Targeting the Substrate: Mechanism-Based Ablation Strategies for Persistent Atrial Fibrillation.

Journal of clinical medicine·2025

Related Experiment Video

Updated: Sep 11, 2025

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection
08:52

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection

Published on: February 17, 2015

9.8K

Sinus node dysfunction in a young patient with Hodgkin lymphoma: a case report.

Gabriela-Elena Marascu1,2, Madalina Schmidt3, Ruxandra Vidlescu1,3

  • 1Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Eroii Sanitari Boulevard, No 8, District 5, Bucharest 050474, Romania.

European Heart Journal. Case Reports
|August 14, 2025
PubMed
Summary

This case report details a young male with Hodgkin lymphoma (HL) who presented with asymptomatic sinus node dysfunction, an early indicator of cardiac involvement. This finding highlights the importance of cardiac monitoring in lymphoma patients.

Keywords:
ArrhythmiaCardiac nuclear imagingCase reportHodgkin lymphomaSinus node dysfunction

More Related Videos

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
09:20

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice

Published on: July 5, 2021

3.2K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

818

Related Experiment Videos

Last Updated: Sep 11, 2025

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection
08:52

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection

Published on: February 17, 2015

9.8K
Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
09:20

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice

Published on: July 5, 2021

3.2K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

818

Area of Science:

  • Cardiology
  • Oncology
  • Electrophysiology

Background:

  • Sinus node dysfunction is a rare bradyarrhythmia in lymphoma patients.
  • It has not been previously reported in individuals with Hodgkin lymphoma (HL).

Observation:

  • A 17-year-old male with stage IV A nodular sclerosis classic type HL presented with asymptomatic sinus node dysfunction.
  • Electrocardiogram revealed intermittent sinus arrest with a junctional rhythm.
  • Imaging studies showed mediastinal adenopathies infiltrating the cardiac structures, including the right atrium and interatrial septum.

Findings:

  • The patient's cardiac conduction and rhythm abnormalities improved with chemotherapy.
  • This suggests a direct link between the lymphoma and cardiac involvement.

Implications:

  • This is the first reported case of Hodgkin lymphoma presenting with sinus node dysfunction as an early sign of cardiac involvement.
  • It underscores the need for vigilance regarding cardiac complications in HL patients.
  • Early detection and management of cardiac issues may improve patient outcomes.