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Published on: January 5, 2024
Effect of cranial electro-stimulation on cognition in perimenopausal women: randomized control study
Naveeta Thakur1, Nidhi Sharma1, Simranjeet Kaur2
1Department of Neurological Physiotherapy, Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed to be University), Mullana (Ambala), Haryana, India.
Objective:
The aim of this study was to investigate the efficacy of cranial electrotherapy stimulation (CES) on cognition among perimenopausal women.
Methods:
The pretest-post-test randomized controlled trial was conducted between April 2024 and January 2025. Forty-six perimenopausal women, aged 40-55 years, were randomized into two groups: active CES (n = 23) or sham CES (n = 23). Participants were blinded to the study. Both groups received 30-min sessions, 4 days a week for 4 weeks. The participants were assessed at baseline and at the end of 4 weeks of intervention using the Montreal Cognitive Assessment (MoCA) scale.
Results:
Demographic and baseline characteristics depicted a normal distribution for both groups, except for MoCA (p < 0.05). Within-group analyses of both groups demonstrated significant differences for MoCA (active CES, p = 0.001; sham CES, p = 0.002) with large effect size ≥ 0.5. Between-group analyses of MoCA showed no significant difference with p = 0.212 and small effect size ≤ 0.3. The time and group interaction effect showed significant improvement with p = 0.001.
Conclusions:
CES has the potential to enhance cognitive function in perimenopausal women. Additionally, no adverse events related to the study were reported.
