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Polymerisation-Induced Self-Assembly on Planar Surfaces: A New Approach for Controlling Surface Topography and
Xin Xu1, Jia-Qi Xu2, You-Liang Zhu2
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Queensland, 4072, Australia.
Angewandte Chemie (International Ed. in English)
|August 14, 2025
Summary
Surface polymerisation-induced self-assembly (PISA) creates novel nanoparticle structures on surfaces. This method controls surface properties for advanced applications like antifouling and drug delivery.
Area of Science:
- Materials Science
- Polymer Chemistry
- Surface Science
Background:
- Polymerisation-induced self-assembly (PISA) is a key technique for creating polymeric nanoparticles.
- Most PISA research focuses on solution-based methods with free macro-stabilisers.
- Surface PISA, using tethered macro-stabilisers, is underexplored but promising.
Purpose of the Study:
- To investigate surface PISA using experimental and computational methods.
- To identify differences between surface PISA and solution-based PISA.
- To demonstrate surface PISA's potential for controlling surface topography and bio-interactions.
Main Methods:
- Exploration of surface PISA through experimental studies.
- Computational modelling to understand surface PISA mechanisms.
- Application of surface PISA for creating functional surfaces.
Main Results:
- Key differences between surface PISA and solution-based PISA were identified.
- Surface PISA enables precise control over surface topography.
- Demonstrated creation of slippery liquid-infused porous surfaces (SLIPS).
Conclusions:
- Surface PISA is a novel and versatile approach for advanced material design.
- Surface PISA can be used to create surfaces with enhanced antifouling and antimicrobial properties.
- This work advances PISA technology and opens new application avenues.
